MDM2-P53 Signaling Pathway-Mediated Upregulation of CDC20 Promotes Progression of Human Diffuse Large B-Cell Lymphoma.

Chengtao SunMengzhen LiYanfen FengFeifei Sun Li ZhangYanjie XuSuying LuJia Zhu Junting HuangJuan WangYang HuYizhuo Zhang

Published in: OncoTargets and therapy (2020)

CDC20 was identified as a key downstream gene of the MDM2-p53 signaling pathway in DLBCL and may be used as a novel target gene to guide therapeutic applications.

Keyphrases

diffuse large b cell lymphoma
signaling pathway
epstein barr virus
pi k akt
copy number
endothelial cells
genome wide
epithelial mesenchymal transition
cell cycle
induced apoptosis
genome wide identification
cell proliferation
poor prognosis
gene expression
induced pluripotent stem cells
long non coding rna