Amiodarone for arrhythmia in patients with Chagas disease: A systematic review and individual patient data meta-analysis.

Cinara Stein Celina Borges MigliavacaVerônica ColpaniPriscila Raupp da RosaDaniel SganzerlaNatalia Elis GiordaniSandro Renê Pinto de Sousa MiguelLuciane Nascimento CruzCarisi Anne PolanczykAntonio Luiz P RibeiroMaicon Falavigna

Published in: PLoS neglected tropical diseases (2018)

Amiodarone is effective in reducing ventricular arrhythmias, but there is no evidence for hard endpoints (sudden death, hospitalization). Although our findings support the use of amiodarone, it is important to balance the potential benefits and harms at the individual level for decision-making.

Keyphrases

systematic review
decision making
catheter ablation
case report
meta analyses
electronic health record
left ventricular
big data
randomized controlled trial
risk assessment
machine learning
artificial intelligence