Development of a genome-scale metabolic model for the lager hybrid yeast S. pastorianus to understand the evolution of metabolic pathways in industrial settings.
Soukaina TimoumaLaura Natalia Balarezo-CisnerosJean-Marc SchwartzDaniela DelneriPublished in: mSystems (2024)
(domestication processes), (ii) aid top-down predictions for strain development (industrial biotechnology), and (iii) allow predictions of evolutionary trajectories of metabolic pathways in aneuploid hybrids (evolutionary genetics).