Maternal Intake of Dietary Fat Pre-Programs Offspring's Gut Ecosystem Altering Colonization Resistance and Immunity to Infectious Colitis in Mice.

Candice QuinSanjoy GhoshChuanbin DaiJacqueline A BarnettAlexander M GarnerRachael K H YooWesley F ZandbergAmy BottaMonika A GorzelakDeanna L Gibson

Published in: Molecular nutrition & food research (2021)

Overall, these data reveal that maternal intake of fatty acids do have transgenerational impacts on their offspring's bacteriome and enteric infection risk. Based on this study, saturated fats should be included in maternal diets.

Keyphrases

birth weight
fatty acid
pregnancy outcomes
weight gain
high fat diet
adipose tissue
public health
climate change
genome wide
electronic health record
risk assessment
type diabetes
body mass index
high fat diet induced
metabolic syndrome
pregnant women
insulin resistance
human health
physical activity