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A 30-s exposure to ethanol 20% is cytotoxic to human keratinocytes: possible mechanistic link between alcohol-containing mouthwashes and oral cancer.

José Manuel Calderón-MontañoJulio José Jiménez-AlonsoEmilio Guillén-MancinaEstefanía Burgos-MorónMiguel López-Lázaro
Published in: Clinical oral investigations (2018)
Many mouthwashes contain percentages of ethanol above 20%. Because ethanol is not crucial to prevent and reduce gingivitis and plaque, members of the dental team should consider the potential risk of oral cancer associated with frequent use of alcohol-containing mouthwashes when advising their patients.
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