Increased Expression Of SOX2 Predicts A Poor Prognosis And Promotes Malignant Phenotypes In Upper Tract Urothelial Carcinoma.

Zhengqing BaoYonghao ZhanShiming HeYifan LiBao GuanQun HeXinyu YangXuesong LiDong FangLiqun Zhou

Published in: Cancer management and research (2019)

SOX2 is an independent prognostic marker of poor DFS and CSS in UTUC patients who have undergone RNU. Moreover, these data suggest that SOX2 may be a promising therapeutic target in UTUC.

Keyphrases

poor prognosis
long non coding rna
transcription factor
stem cells
end stage renal disease
newly diagnosed
peritoneal dialysis
prognostic factors
electronic health record
machine learning
binding protein
patient reported outcomes