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Universal strategy for preimplantation genetic testing for cystic fibrosis based on next generation sequencing.

Sandrine ChamayouMaria SicaliDebora LombardoCarmelita AlecciCarmen RagoliaElena MagliaAnnalisa LiprinoClementina CardeaGiorgia StoraciSimona RomanoAntonino Guglielmino
Published in: Journal of assisted reproduction and genetics (2019)
The present protocol based on the entire CFTR gene together with informative SNPs outside and inside the gene can be applied to diagnose all CF mutations at preimplantation stage.
Keyphrases
  • cystic fibrosis
  • copy number
  • genome wide
  • pseudomonas aeruginosa
  • lung function
  • randomized controlled trial
  • genome wide identification
  • air pollution
  • cell free