Development of a multigenomic liquid biopsy (PROSTest) for prostate cancer in whole blood.

Irvin M ModlinMark KiddIgnat A DrozdovMartin BoegemannLisa BodeiJolanta KunikowskaAnna MalczewskaChristof BernemannSrinivas V KoduruKambiz Rahbar

Published in: The Prostate (2024)

A 27-gene whole blood signature for PCa is concordant with tissue mRNA levels. Measuring blood expression provides a minimally invasive genomic tool that may facilitate prostate cancer management.

Keyphrases

prostate cancer
minimally invasive
radical prostatectomy
copy number
poor prognosis
binding protein
genome wide
ultrasound guided
ionic liquid
gene expression
long non coding rna
robot assisted
fine needle aspiration
dna methylation
genome wide identification
transcription factor