Identification of hub genes related to Duchenne muscular dystrophy by weighted gene co-expression network analysis.
Yanning WeiQisheng SuXiaohong LiPublished in: Medicine (2023)
SERPING1, F13A1, C1S, C1R, and HLA-DPA1 may participate in the development of DMD by regulating innate immunity and inflammation, and they are expected to be a potential biomarker and novel therapeutic targets for DMD.
Keyphrases
- duchenne muscular dystrophy
- network analysis
- bioinformatics analysis
- genome wide
- genome wide identification
- poor prognosis
- oxidative stress
- muscular dystrophy
- copy number
- genome wide analysis
- dna methylation
- transcription factor
- binding protein
- long non coding rna
- magnetic resonance
- computed tomography
- gene expression
- magnetic resonance imaging