Multi-arm Trial of Inflammatory Signal Inhibitors (MATIS) for hospitalised patients with mild or moderate COVID-19 pneumonia: a structured summary of a study protocol for a randomised controlled trial.

Nikhil VergisRachel PhillipsVictoria CorneliusAlexia KatsarouTaryn YoungsteinLucy CookMichelle WillicombeClio PilayTina ShturovaMelanie AlmonteAsad CharaniaRichard TurnerOnn Min KonGraham CookeMark ThurszSvetlana CherlinJames WasonDragana MilojkovicAndew J InnesNichola Cooper

Published in: Trials (2021)

EudraCT: 2020-001750-22 , 9th July 2020 ClinicalTrials.gov: NCT04581954 , 9th October 2020 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest of expediting dissemination of this material, familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol.

Keyphrases

randomized controlled trial
coronavirus disease
sars cov
study protocol
clinical trial
phase iii
high intensity
phase ii
mechanical ventilation