Enhancing systematic reviews in orthodontics: a comparative examination of GPT-3.5 and GPT-4 for generating PICO-based queries with tailored prompts and configurations.

Both ChatGPT 3.5 and 4 can be pivotal tools for generating PICO-driven queries in orthodontics when optimally configured. However, the precision required in medical research necessitates a judicious and critical evaluation of LLM-generated outputs, advocating for a circumspect integration into scientific investigations.