Tolypocladium sinense Mycelium Polysaccharide Alleviates Obesity, Lipid Metabolism Disorder, and Inflammation Caused by High Fat Diet via Improving Intestinal Barrier and Modulating Gut Microbiota.

Mingjian BaiXiaolong WangDongyang LiuAofeng XuHao ChengLin LiChunjing Zhang

Published in: Molecular nutrition & food research (2024)

The findings show that TSMP can inhibit obesity and alleviates obesity-related lipid metabolism disorders, inflammatory responses, and oxidative stress by modulating the gut microbiota and improving intestinal barrier.

Keyphrases

insulin resistance
high fat diet
oxidative stress
metabolic syndrome
weight loss
high fat diet induced
type diabetes
adipose tissue
weight gain
skeletal muscle
signaling pathway
mouse model
dna damage
body mass index
fatty acid