Microvascular remodeling and altered angiogenic signaling in human kidneys distal to occlusive atherosclerotic renal artery stenosis.
Nattawat KlomjitXiang-Yang ZhuAlfonso EirinAditya S PawarSabena M ConleyAmrutesh S PuranikChristopher M FergusonSeo Rin KimHui TangKyra L JordanIshran M SaadiqAmir LermanJoseph P GrandeStephen C TextorLilach Orly LermanPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2022)
These observations underscore the nature of human RAS as a microvascular disease distal to main vessel stenosis and support therapeutic strategies directly targeting the poststenotic kidney microcirculation in patients with RAS.