Genetic variations in DNA repair gene NEIL1 associated with radiation pneumonitis risk in lung cancer patients.

Yuming ZhengLeizhen ZhengJiahua YuMawei JiangSongfang ZhangXuwei Cai Meiling Zhu

Published in: Molecular genetics & genomic medicine (2021)

Genetic variants of NEIL1 are associated with RP risk through regulation of NEIL1 expression and serve as independent biomarkers for prediction of RP in patients treated with thoracic radiotherapy.

Keyphrases

dna repair
dna damage
genome wide
poor prognosis
copy number
early stage
spinal cord
radiation induced
radiation therapy
dna damage response
squamous cell carcinoma
gene expression
dna methylation
rheumatoid arthritis
oxidative stress
spinal cord injury