Intrathecal cytokine profile in neuropathy with anti-neurofascin 155 antibody.

Hidenori OgataXu ZhangRyo YamasakiTakayuki FujiiAkira MachidaNobutoshi MorimotoKenichi KaidaTeruaki MasudaYukio AndoMotoi KuwaharaSusumu KusunokiYuri NakamuraTakuya MatsushitaNoriko IsobeJun-Ichi Kira

Published in: Annals of clinical and translational neurology (2019)

Intrathecal upregulation of type 2 helper T (Th2) cell cytokines is characteristic of IgG4 NF155+ CIDP, while type 1 helper T cell cytokines are increased in CIDP regardless of the presence or absence of anti-NF155 antibodies, suggesting that overproduction of Th2 cell cytokines is unique to NF155+ CIDP.

Keyphrases

signaling pathway
lps induced
single cell
pi k akt
oxidative stress
nuclear factor
cell therapy
regulatory t cells
dendritic cells
cell proliferation
poor prognosis
immune response
mesenchymal stem cells
toll like receptor
long non coding rna