Multiple Omics Analysis of the Role of RBM10 Gene Instability in Immune Regulation and Drug Sensitivity in Patients with Lung Adenocarcinoma (LUAD).
Liusheng WuQi LiuXin RuanXinyu LuanYanfeng ZhongJixian LiuJun YanXiaoqiang LiPublished in: Biomedicines (2023)
RBM10 can inhibit the proliferation and invasion of lung adenocarcinoma cells through negative regulation and promote the apoptosis of lung adenocarcinoma cells through immunomodulatory mechanisms. The expression level of RBM10 affects the efficacy of targeted drug therapy and the survival prognosis of lung adenocarcinoma patients, which has a certain guiding significance for the clinical treatment of these patients.
Keyphrases
- end stage renal disease
- cell cycle arrest
- induced apoptosis
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- oxidative stress
- endoplasmic reticulum stress
- poor prognosis
- transcription factor
- drug delivery
- signaling pathway
- dna methylation
- bone marrow
- adverse drug
- electronic health record