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Synchronous or collision solid neoplasms and lymphomas: A systematic review of 308 case reports.

Rafael Parra-MedinaFranky RochaJuan Pablo Castañeda-GonzálezPaula Moreno-LuceroLuis VelozaAlfredo E Romero-Rojas
Published in: Medicine (2022)
The frequent association of some type of B-cell lymphoma and adenocarcinoma in synchronous/collision tumors of the gastrointestinal tract points to common pathogenic mechanisms in both neoplasia, particularly related to chronic inflammation in this location. In most cases, lymphoma identified in locoregional lymph nodes or distant of a carcinoma seems to represent an incidental finding during the carcinoma diagnostic/therapeutic approach. A synergy between carcinoma and lymphoma (involving inflammation and immunosuppression mechanisms) may favor tumor progression and dissemination. A better understating of the interactions lymphoma/carcinoma in the setting of synchronous/collision tumors may help to improve patient management and prognosis.
Keyphrases
  • diffuse large b cell lymphoma
  • lymph node
  • oxidative stress
  • case report
  • high grade
  • poor prognosis
  • early stage
  • long non coding rna
  • rectal cancer
  • sentinel lymph node