Differential unfolded protein response in skeletal muscle from non-diabetic glucose tolerant or intolerant patients with obesity before and after bariatric surgery.
Camille MarciniakChristian DuhemAlexis BoulinguiezVioleta RaverdyGregory BaudHélène VerkindtRobert CaiazzoBart StaelsHélène DuezFrancois PattouSteve LancelPublished in: Acta diabetologica (2020)
CHOP and ATF6 expression decreased in non-diabetic GI patients with obesity and was modified by bariatric surgery. These genes may contribute to glucose homeostasis in human skeletal muscle.
Keyphrases
- skeletal muscle
- insulin resistance
- weight loss
- type diabetes
- bariatric surgery
- metabolic syndrome
- high fat diet induced
- endothelial cells
- endoplasmic reticulum stress
- wound healing
- poor prognosis
- blood glucose
- adipose tissue
- weight gain
- obese patients
- binding protein
- genome wide
- diffuse large b cell lymphoma
- transcription factor
- induced pluripotent stem cells
- glycemic control
- protein protein
- blood pressure
- dna methylation
- genome wide identification