Effect of nitric oxide on postoperative acute kidney injury in patients who underwent cardiopulmonary bypass: a systematic review and meta-analysis with trial sequential analysis.

Jie HuStefano SpinaFrancesco ZadekNikolay O KamenshchikovEdward A BittnerJuan PedemonteLorenzo Berra

Published in: Annals of intensive care (2019)

NO appeared to reduce the risk of postoperative AKI in patients undergoing CPB. Additional studies are required to ascertain the finding and further determine the dosage, timing and duration of NO administration.

Keyphrases

patients undergoing
nitric oxide
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
acute kidney injury
peritoneal dialysis
prognostic factors
hydrogen peroxide
randomized controlled trial
nitric oxide synthase
patient reported outcomes
phase ii