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Formulation and Characterization of Phytostanol Ester Solid Lipid Nanoparticles for the Management of Hypercholesterolemia: An ex vivo Study.

Sony Chandi ShresthaKebreab GhebremeskelKenneth N WhiteCaterina MinelliIhab TewfikPanna ThapaSundus Tewfik
Published in: International journal of nanomedicine (2021)
Phytostanol ester solid lipid nanoparticles were successfully formulated and characterized. The formulation has the potential to provide an innovative drug delivery system for phytostanols which reduce cholesterol and have a potentially ideal safety profile. This can contribute to better management of one of the main risk factors of cardiovascular diseases.
Keyphrases
  • risk factors
  • cardiovascular disease
  • drug delivery
  • fatty acid
  • low density lipoprotein
  • type diabetes
  • metabolic syndrome