Genome analysis of Salmonella enterica subsp. diarizonae isolates from invasive human infections reveals enrichment of virulence-related functions in lineage ST1256.
Joaquín Giner-LamiaPablo VinuesaLaura BetancorClaudia SilvaJulieta BisioLorena SoletoJosé A ChabalgoityJosé Luis Puentenull nullFrancisco García-Del PortilloPublished in: BMC genomics (2019)
The comparative genomic study of two diarizonae strains isolated in Bolivia from human patients uncovered the presence of many genes putatively related to virulence. The statistically-significant acquisition of a unique combination of these functions by diarizonae strains isolated from humans may have impacted the ability of these isolates to successfully infect the human host.
Keyphrases
- endothelial cells
- escherichia coli
- induced pluripotent stem cells
- pseudomonas aeruginosa
- staphylococcus aureus
- pluripotent stem cells
- end stage renal disease
- newly diagnosed
- ejection fraction
- gene expression
- chronic kidney disease
- antimicrobial resistance
- cystic fibrosis
- copy number
- patient reported outcomes
- peritoneal dialysis
- cell fate