Focal dose escalation for prostate cancer using 68Ga-HBED-CC PSMA PET/CT and MRI: a planning study based on histology reference.

Constantinos ZamboglouBenedikt ThomannKhodor KoubarPeter BronsertTobias KraussHans C RischkeIlias SachpazidisVanessa DrendelNasr SalmanKathrin ReichelCordula A JilgMartin WernerPhilipp T MeyerMichael BockDimos BaltasAnca L Grosu

Published in: Radiation oncology (London, England) (2018)

IMRT dose escalation on GTVs based on mpMRI, PSMA PET/CT and the combination of both was feasible. Boosting GTV-union resulted in significantly higher TCP-histo with no or minimal increase of NTCPs compared to the other plans.

Keyphrases

pet ct
prostate cancer
positron emission tomography
open label
magnetic resonance imaging
radical prostatectomy
contrast enhanced
health insurance
clinical trial
randomized controlled trial
diffusion weighted imaging
pet imaging