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"Omics" data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy.

Nzali V CampbellDavid A WeitzenkampIan L CampbellRonald F SchmidtChindo HicksMichael J MorganDavid C IrwinJohn J Tentler
Published in: BMC medical genomics (2018)
We introduce an integrative data strategy that considers the interplay between the DNA, mRNA, and associated pathways, which represents a possible diagnostic, prognostic, biomarker, and personalized treatment discovery approach in genomically heterogeneous diseases.
Keyphrases
  • electronic health record
  • big data
  • small molecule
  • circulating tumor
  • high throughput
  • single cell
  • single molecule
  • emergency department
  • fatty acid
  • data analysis
  • combination therapy
  • adverse drug