"Omics" data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy.

Nzali V CampbellDavid A WeitzenkampIan L CampbellRonald F SchmidtChindo HicksMichael J MorganDavid C IrwinJohn J Tentler

Published in: BMC medical genomics (2018)

We introduce an integrative data strategy that considers the interplay between the DNA, mRNA, and associated pathways, which represents a possible diagnostic, prognostic, biomarker, and personalized treatment discovery approach in genomically heterogeneous diseases.

Keyphrases

electronic health record
big data
small molecule
circulating tumor
high throughput
single cell
single molecule
emergency department
fatty acid
data analysis
combination therapy
adverse drug