Differences in the risk of immune-related pneumonitis between PD-1 and PD-L1 inhibitors: a meta-analysis according to the new mirror-principle and PRISMA guidelines.

Yuan TianZongxiu YinChi ZhangZhuoqi LiYuanyuan WangKai ZhangFeng ChenQi Dang

Published in: Cancer immunology, immunotherapy : CII (2024)

Both PD-1 and PD-L1 inhibitors increased the risk of immune-related pneumonitis, while the risk of PD-1-induced pneumonitis was significantly higher than that of PD-L1 inhibitors.

Keyphrases

interstitial lung disease
drug induced
high glucose
systemic sclerosis
systematic review
clinical practice
randomized controlled trial
diabetic rats
oxidative stress
rheumatoid arthritis