Role of FOLFIRINOX and chemoradiotherapy in locally advanced and borderline resectable pancreatic adenocarcinoma: update of the AGEO cohort.

Edouard AuclinLysiane MartheyRaef AbdallahLéo MasEric FrancoisAngélique SaintAntonio Sa CunhaAngélique VienotThierry LecomteVincent HautefeuilleChristelle De La FouchardièreMatthieu SarabiFeryel KsontiniJulien ForestierRomain CoriatEmmanuelle FabianoFlorence LeroyNicolas WillietJean-Baptiste BachetDavid TougeronGilles Manceau

Published in: British journal of cancer (2021)

FOLFIRINOX for LAPA and BRPA seems to be effective with a manageable toxicity profile. These promising results in "real-life" patients now have to be confirmed in a Phase 3 randomised trial.

Keyphrases

locally advanced
rectal cancer
neoadjuvant chemotherapy
squamous cell carcinoma
radiation therapy
phase ii study
end stage renal disease
chronic kidney disease
ejection fraction
randomized controlled trial
oxidative stress
clinical trial
patient reported outcomes