Expression and prognosis of DSG-2, CXADR, CD46 in head and neck squamous cell carcinoma.

Inga Marte Charlott SeutheLea KrauseMarkus RuweSteffi SillingAnja EhrhardtSabine EichhornEric Ehrke-SchulzJonas Jae-Hyun Park

Published in: Pathology, research and practice (2024)

No prognostic significance of the expression of DSG-2, CXADR or CD46 in HNSCC was seen. DSG-2, CXADR and CD46 are expressed in HNSCC, so that optimization of oncotherapy with adenoviral vectors appears promising. Due to the significantly increased expression of DSG-2 and CXADR in advanced OPSCC tumors, there is potential for optimizing oncotherapy here in particular.

Keyphrases

poor prognosis
binding protein
long non coding rna
nk cells
risk assessment
gene therapy