Upregulation of proteins of the NLRP3 inflammasome in patients with periodontitis and uncontrolled type 2 diabetes.
Ana Lilia García-HernándezÁngel Enrique Muñoz-SaavedraPatricia González-AlvaLeticia Moreno-FierrosFulgencio Eduardo Llamosas-HernándezSaul Ernesto Cifuentes-MendiolaNestor Rubio-InfantePublished in: Oral diseases (2018)
The upregulation of genes and proteins involved in the activation of the NLRP3 inflammasome components in patients with periodontitis and uncontrolled T2D suggests a possible role in the more severe pathological processes leading to destruction of periodontal tissues observed in these patients.
Keyphrases
- nlrp inflammasome
- type diabetes
- end stage renal disease
- ejection fraction
- poor prognosis
- chronic kidney disease
- newly diagnosed
- cell proliferation
- gene expression
- signaling pathway
- peritoneal dialysis
- genome wide
- early onset
- prognostic factors
- insulin resistance
- glycemic control
- dna methylation
- drug induced
- genome wide identification
- genome wide analysis