Neutralizing antibody to proNGF rescues erectile function by regulating the expression of neurotrophic and angiogenic factors in a mouse model of cavernous nerve injury.
Doo Yong ChungKang-Moon SongMin-Ji ChoiAnita LimanjayaKalyan GhatakJiyeon OckGuo Nan YinChang Hee HongSoon-Sun HongJun Kyu SuhJi Kan RyuPublished in: Andrology (2020)
The preservation of damaged cavernous neurovasculature through inhibition of the proNGF/p75NTR pathway may be a novel strategy to treat radical prostatectomy-induced erectile dysfunction.