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IL-6/STAT3 signaling pathway induces prostate apoptosis response protein-4(PAR-4) to stimulate malignant behaviors of hepatocellular carcinoma cells.
Junnv Xu
Kun Liu
Zhixun Gong
Jinchen Liu
Haifeng Lin
Bo Lin
Wei Li
Mingyue Zhu
Mengsen Li
Published in:
Annals of hepatology (2024)
PAR-4 expression is positively correlated with HCC; PAR-4 promotes malignant behavior of HCC cells mediated by the IL-6/STAT3 signaling pathway.
Keyphrases
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cell cycle arrest
pi k akt
signaling pathway
induced apoptosis
cell proliferation
endoplasmic reticulum stress
oxidative stress
prostate cancer
cell death
poor prognosis
epithelial mesenchymal transition
binding protein
amino acid
long non coding rna