Clinical Trial Registry Use in Orthopaedic Surgery Systematic Reviews.

Arjun K Reddy J Michael Anderson Harrison M Gray Keith Fishbeck Matt Vassar

Published in: The Journal of bone and joint surgery. American volume (2021)

The exclusion of clinical trial registry searches potentially contributes to publication bias within the orthopaedic literature. Moving forward, systematic review authors should include clinical trial registry searches for unpublished clinical trial data to provide the most accurate representation of the available evidence for systematic reviews and meta-analyses.

Keyphrases

clinical trial
meta analyses
systematic review
phase ii
randomized controlled trial
open label
double blind
study protocol
phase iii
minimally invasive
high resolution
machine learning
atrial fibrillation
percutaneous coronary intervention
big data
artificial intelligence