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Molecular interactions of miR-338 during tumor progression and metastasis.

Meysam Moghbeli
Published in: Cellular & molecular biology letters (2021)
It was concluded that miR-338 mainly functions as a tumor suppressor in different cancers. There were also significant associations between miR-338 and other ncRNAs in tumor cells. Moreover, miR-338 has a pivotal role during tumor progression using the regulation of WNT, MAPK, and PI3K/AKT signaling pathways. This review highlights miR-338 as a pivotal ncRNA in biology of tumor cells.
Keyphrases
  • cell proliferation
  • pi k akt
  • long non coding rna
  • signaling pathway
  • long noncoding rna
  • poor prognosis
  • stem cells
  • oxidative stress
  • cell cycle arrest
  • childhood cancer