Investigating optimal β-cell-preserving treatment in latent autoimmune diabetes in adults: Results from a 21-month randomized trial.
Ingrid K HalsHanne Fiskvik FleinerNina ReimersMarianne C AstorKarin FilipssonZuheng MaValdemar GrillAnneli BjörklundPublished in: Diabetes, obesity & metabolism (2019)
β-cell function after intervention was similar in patients with insulin- and sitagliptin-treated LADA, regardless of the strength of autoimmunity. Further, participants with low levels of GAD antibodies did not experience progressive deterioration of β-cell function over a 21-month period. Taken together, these findings could be useful for clinicians' choices of treatment in people with LADA.