A systematic review and meta-analysis of the efficacy of ketamine and esketamine on suicidal ideation in treatment-resistant depression.

Ya-Ting WangXiao-Le WangLan LeiZhen-Yu GuoFei-Fei KanDie HuCong GaiYi Zhang

Published in: European journal of clinical pharmacology (2023)

This meta-analysis suggested that esketamine and ketamine have failed to reduce suicidal ideation in patients with TRD. Further studies are desirable to confirm the effects of ketamine and esketamine in TRD patients.

Keyphrases

systematic review
end stage renal disease
pain management
ejection fraction
newly diagnosed
chronic kidney disease
case control
peritoneal dialysis
prognostic factors
randomized controlled trial
patient reported outcomes
sleep quality
chronic pain