Effectiveness of a two-step population-based osteoporosis screening program using FRAX: the randomized Risk-stratified Osteoporosis Strategy Evaluation (ROSE) study.

Katrine Hass RubinM J RothmannT HolmbergM HøibergS MöllerR BarkmannC C GlüerA P HermannM BechJ GramK Brixen

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2017)

Compared to an office-based case-finding strategy, the two-step systematic screening strategy had no overall effect on fracture incidence. The two-step strategy seemed, however, to be beneficial in the group of women who were identified by FRAX as moderate- or high-risk patients and complied with DXA.

Keyphrases

bone mineral density
postmenopausal women
end stage renal disease
newly diagnosed
randomized controlled trial
ejection fraction
systematic review
body composition
double blind
magnetic resonance imaging
risk factors
prognostic factors
quality improvement
metabolic syndrome
placebo controlled
study protocol