A Retrospective Analysis of the De Ritis Ratio in Muscle Invasive Bladder Cancer, with Focus on Tumor Response and Long-Term Survival in Patients Receiving Neoadjuvant Chemotherapy and in Chemo Naïve Cystectomy Patients-A Study of a Clinical Multicentre Database.
Victoria ErikssonOscar HolmkvistYlva HugeMarkus JohanssonFarhood AlamdariJohan SvenssonFiras AljaberyAmir SherifPublished in: Journal of personalized medicine (2022)
A high pre-treatment De Ritis ratio is on a population level, associated with increased mortality post-RC in endpoints DFS, CSS and OS. Associations decrease over time and require further investigations to determine how strong the associations are as meaningful prognostic markers for long-term mortality in MIBC. The ratio is not suitable for downstaging-prediction.
Keyphrases
- risk factors
- neoadjuvant chemotherapy
- locally advanced
- end stage renal disease
- muscle invasive bladder cancer
- lymph node
- ejection fraction
- chronic kidney disease
- newly diagnosed
- sentinel lymph node
- peritoneal dialysis
- rectal cancer
- photodynamic therapy
- clinical trial
- prognostic factors
- randomized controlled trial
- squamous cell carcinoma
- radiation therapy
- combination therapy
- study protocol
- cardiovascular events
- robot assisted
- cancer therapy
- smoking cessation
- adverse drug
- replacement therapy
- double blind