Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study.
Eleanor L WattsTomas I GonzalesTessa StrainPedro F Saint-MauriceD Timothy Timothy BishopStephen J ChanockMattias J JohanssonTemitope O KekuLoic Le MarchandVictor MorenoPolly A NewcombChristina C NewtonRish K PaiMark P PurdueCornelia M UlrichKarl Smith-ByrneBethany Van Guelpennull nullFelix R DayKatrien WijndaeleNicholas J WarehamCharles E MatthewsSteven C MooreSoren BragePublished in: British journal of cancer (2023)
Higher fitness levels may reduce risks of endometrial, colorectal, and breast cancer, though relationships with adiposity are complex and may mediate these relationships. Increasing fitness, including via changes in body composition, may be an effective strategy for cancer prevention.
Keyphrases
- body composition
- papillary thyroid
- resistance training
- bone mineral density
- squamous cell
- physical activity
- cross sectional
- lymph node metastasis
- insulin resistance
- gene expression
- genome wide
- risk assessment
- type diabetes
- body mass index
- squamous cell carcinoma
- human health
- young adults
- postmenopausal women
- skeletal muscle