Do the change in β-hCG values between the 0th and 4th days in tubal ectopic pregnancy treatment with a single-dose methotrexate (MTX) protocol predict the need for a second dose of MTX?

Yıldız Akdaş Reis Arife Akay Merve Özkan Fahri Burcin Firatligil Murat Levent Dereli Tugba Kinay Salim Erkaya

Published in: Archives of gynecology and obstetrics (2023)

The single-dose MTX protocol is successful in 83.3% of convenient cases (as the control group), but an increase of 20% in β-hCG between days 0 and 4 predicts the patients who need to be administered second-dose MTX, and thus, a double-dose MTX protocol will be achieved early.

Keyphrases

randomized controlled trial
high dose
low dose
pregnant women