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Lymphocyte activation gene (LAG)-3 is a potential immunotherapeutic target for microsatellite stable, programmed death-ligand 1 (PD-L1)-positive endometrioid endometrial cancer.

Jin Hwa HongHyun Woong ChoYung Taek OuhJae Kwan LeeYikyeong Chun
Published in: Journal of gynecologic oncology (2022)
In patients with MSS EC harboring PD-L1, LAG-3 may be a potential immunotherapeutic target. Clinical trials investigating the role of anti-LAG-3 antibodies, alone or in combination with other immunotherapies, are warranted.
Keyphrases
  • endometrial cancer
  • clinical trial
  • human health
  • genome wide
  • randomized controlled trial
  • gene expression
  • risk assessment
  • phase ii
  • phase iii
  • clear cell