Impact of aortic valve replacement in symptomatic low-risk patients with less than severe aortic stenosis.
Saki ItoRoger LahamVuyisile T NkomoJohn K ForrestMichael J ReardonStephen H LittleMubashir MumtazHemal GadaTanvir BajwaDavid LangholzJohn HeiserAtul ChawlaBart JensonGuilherme AttizanniAlan H MarkowitzJian HuangJae K OhPublished in: Open heart (2023)
In symptomatic patients with moderately-severe AS, AVR appears to be beneficial. Determination of the clinical and haemodynamic profile of patients who can benefit from earlier isolated AVR needs further investigation in randomised clinical trials.
Keyphrases
- aortic valve replacement
- aortic stenosis
- clinical trial
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- aortic valve
- ejection fraction
- left ventricular
- early onset
- coronary artery disease
- open label
- double blind
- phase ii
- randomized controlled trial
- drug induced
- placebo controlled
- solid phase extraction
- molecularly imprinted
- heart failure
- liquid chromatography