Login / Signup

Modelling alcohol consumption in rodents using two-bottle choice home cage drinking and optional lickometry-based microstructural analysis.

Shikun HouNathaly M Arce SotoElizabeth J Glover
Published in: bioRxiv : the preprint server for biology (2024)
This protocol describes a standard intermittent-access two-bottle choice home cage drinking paradigm to model alcohol consumption in rats. In addition, it provides step-by-step instructions to augment the standard protocol with a DIY lickometer system that enables microstructural analysis of drinking behavior.
Keyphrases
  • alcohol consumption
  • white matter
  • randomized controlled trial
  • healthcare
  • decision making
  • high intensity
  • multiple sclerosis