Modelling alcohol consumption in rodents using two-bottle choice home cage drinking and optional lickometry-based microstructural analysis.

Shikun HouNathaly M Arce SotoElizabeth J Glover

Published in: bioRxiv : the preprint server for biology (2024)

This protocol describes a standard intermittent-access two-bottle choice home cage drinking paradigm to model alcohol consumption in rats. In addition, it provides step-by-step instructions to augment the standard protocol with a DIY lickometer system that enables microstructural analysis of drinking behavior.

Keyphrases

alcohol consumption
white matter
randomized controlled trial
healthcare
decision making
high intensity
multiple sclerosis