Targeting constitutively active STAT3 in chronic lymphocytic leukemia: A clinical trial of the STAT3 inhibitor pyrimethamine with pharmacodynamic analyses.

Jennifer R BrownSarah R WalkerLisa N HepplerSvitlana TyekuchevaErik A NelsonJosephine KlitgaardMaria NicolaisYasmin KrollMichael XiangJennifer E YehMousumi ChaudhuryZachary T GiacconeStacey M FernandesEric D JacobsenDavid C FisherArnold S FreedmanMatthew S DavidsJeffrey G SupkoCatherine WuDavid A Frank

Published in: American journal of hematology (2021)

Keyphrases

chronic lymphocytic leukemia
clinical trial
cell proliferation
phase ii
cancer therapy
study protocol
open label
randomized controlled trial
double blind