Diagnostic Accuracy of DNA-Methylation in Detection of Cervical Dysplasia: Findings from a Population-Based Screening Program.

Narcisa Muresu Mariangela Valentina Puci Giovanni Sotgiu Illari SechiManuela UsaiAndrea CossuMarianna Martinelli Cocuzza Clementina Elvezia Andrea Fausto Piana

Published in: Cancers (2024)

Overall, we found a good specificity of DNA methylation in comparison to currently used techniques. Further larger studies could support the use of FAM19A4/miR124-2 as reliable biomarkers in the prevention of cervical cancer as triage in the screening protocol.

Keyphrases

dna methylation
genome wide
gene expression
emergency department
cell proliferation
randomized controlled trial
quality improvement
copy number
loop mediated isothermal amplification
sensitive detection