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Efficacy of prolonged-release fampridine versus placebo on walking ability, dynamic and static balance, physical impact of multiple sclerosis, and quality of life: an integrated analysis of MOBILE and ENHANCE.

Raymond HuppertsClaudio GasperiniJan N LyckeTjalf ZiemssenPeter FeysShan XiaoCarlos AcostaThijs KosterJeremy Hobart
Published in: Therapeutic advances in neurological disorders (2022)
The pooled analysis of MOBILE and ENHANCE confirms previous evidence that treatment with PR-fampridine results in clinically meaningful improvements in walking, mobility and balance, self-reported physical impact of MS, and quality of life and is effective across a broad range of PwMS.
Keyphrases
  • multiple sclerosis
  • physical activity
  • mental health
  • mass spectrometry
  • lower limb
  • ms ms
  • phase iii
  • white matter
  • clinical trial
  • combination therapy
  • randomized controlled trial
  • replacement therapy
  • open label