NIH Toolbox performance of persons with Parkinson's disease according to GBA1 and STN-DBS status.

Ahmad AlmelegySrujanesh GundaSteven BuyskeMarc RosenbaumSepehr SaniMitra AfshariLeo V MetmanChristopher G Goetz Deborah A HallM Maral MouradianGian D Pal

Published in: Annals of clinical and translational neurology (2024)

PwP who carry GBA1 mutations and have STN-DBS have greater impaired response inhibition compared with PwP with STN-DBS but without GBA1 mutations. Longitudinal data, including preoperative scores, are required to definitively determine whether GBA1 mutation carriers respond differently to STN-DBS, particularly in the domain of response inhibition.

Keyphrases

deep brain stimulation
patients undergoing
cross sectional
electronic health record
big data
deep learning