Regulatory roles of differentially expressed MicroRNAs in metabolic processes in negative Lens-induced myopia Guinea pigs.

Dadong GuoMeihua DingXiaoli SongYuanyuan SunGuoping LiZonghong LiHuixia WeiJianfeng WuWenjun JiangHongsheng Bi

Published in: BMC genomics (2020)

Our findings indicate that the development of myopia is mainly involved in the disorder of metabolic processes in NLIM guinea pigs. The PPAR signaling, pyruvate and propanoate metabolism pathways may play roles in the development of myopia.

Keyphrases

optic nerve
high glucose
transcription factor
insulin resistance
type diabetes
adipose tissue
metabolic syndrome
endothelial cells
fatty acid
stress induced