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Radiogenomic biomarkers for immunotherapy in glioblastoma: A systematic review of magnetic resonance imaging studies.

Prajwal GhimireBen KinnersleyGolestan KaramiPrabhu ArumugamRichard S HoulstonKeyoumars AshkanMarc ModatThomas C Booth
Published in: Neuro-oncology advances (2024)
Radiogenomic immune biomarkers have the potential to provide early treatment options to patients with glioblastoma. Targeted immunotherapy, stratified by these biomarkers, has the potential to allow individualized neo-adjuvant precision treatment options in clinical trials. However, there are no prospective studies validating these biomarkers, and interpretation is limited due to study bias with little evidence of generalizability.
Keyphrases
  • magnetic resonance imaging
  • clinical trial
  • computed tomography
  • randomized controlled trial
  • case control
  • human health
  • cancer therapy
  • drug delivery
  • climate change
  • diffusion weighted imaging