The Impact of Burst Motor Cortex Stimulation on Cardiovascular Autonomic Modulation in Chronic Pain: A Feasibility Study for a New Approach to Objectively Monitor Therapeutic Effects.
Matthias C BoruttaJulia KoehnDaniela Souza de OliveiraAlessandro Del VecchioTobias EngelhornStefan SchwabMichael BuchfelderThomas M M KinfePublished in: Pain and therapy (2023)
Four months of adjunctive burstMCS was associated with an increase in parameters reflecting both total and parasympathetic autonomic modulation and baroreceptor reflex sensitivity. In contrast, sympathetic tone declined in our three patients, suggesting stimulation-associated improvement not only in subjectively perceived VAS pain scores, but also in objectifiable parameters of autonomic cardiovascular modulation.
Keyphrases
- chronic pain
- heart rate variability
- heart rate
- end stage renal disease
- physical activity
- pain management
- ejection fraction
- newly diagnosed
- chronic kidney disease
- magnetic resonance
- prognostic factors
- peritoneal dialysis
- mental health
- social support
- patient reported outcomes
- magnetic resonance imaging
- computed tomography
- spinal cord injury
- patient reported