The new 2019-EULAR/ACR classification criteria specific domains at diagnosis can predict damage accrual in 670 childhood-onset systemic lupus erythematosus patients.
Ana C PittaClovis Artur Almeida da SilvaCarlos E InsfránSandra G PasotoVitor C TrindadeGlaucia V NovakAna P SakamotoMaria T TerreriRosa Maria Rodrigues PereiraClaudia S MagalhãesAdriana R FonsecaAline G IslabãoAna Pl AssadIzabel M BuscattiAdriana M EliasDaniela P PiottoVirginia P FerrianiLuciana M CarvalhoCarlos N Rabelo JuniorRoberto MariniFlavio R SztajnbokSilvana B SacchettiBlanca E BicaAna J MoraesTeresa C RobazziSimone LotufoAndre S CavalcantiErica N NakaMagda Carneiro-SampaioEloisa S BonfaNádia Emi Aikawanull nullPublished in: Lupus (2021)
The 2019-EULAR/ACR criteria at diagnosis were associated with a higher rate of early damage in cSLE patients, especially for renal and neuropsychiatric damage. Of note, damage was particularly associated with high disease activity at diagnosis and 2019-EULAR/ACR score >25.
Keyphrases
- systemic lupus erythematosus
- disease activity
- end stage renal disease
- oxidative stress
- newly diagnosed
- ejection fraction
- rheumatoid arthritis
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- machine learning
- ankylosing spondylitis
- patient reported outcomes
- rheumatoid arthritis patients
- deep learning
- childhood cancer