Multi-drug resistant Enterobacter bugandensis species isolated from the International Space Station and comparative genomic analyses with human pathogenic strains.
Nitin K SinghDaniela BezdanAleksandra Checinska SielaffKevin WheelerChristopher E MasonKasthuri VenkateswaranPublished in: BMC microbiology (2018)
Given the MDR results for these ISS Enterobacter genomes and increased chance of pathogenicity (PathogenFinder algorithm with > 79% probability), these species pose important health considerations for future missions. Thorough genomic characterization of the strains isolated from ISS can help to understand the pathogenic potential, and inform future missions, but analyzing them in in-vivo systems is required to discern the influence of microgravity on their pathogenicity.
Keyphrases
- drug resistant
- multidrug resistant
- acinetobacter baumannii
- escherichia coli
- current status
- endothelial cells
- copy number
- biofilm formation
- healthcare
- public health
- mental health
- human health
- deep learning
- induced pluripotent stem cells
- health information
- pseudomonas aeruginosa
- pluripotent stem cells
- risk assessment
- dna methylation
- cystic fibrosis