Changes in Biomarker Status in Metastatic Breast Cancer and Their Prognostic Value.
Ji Won WooYul Ri ChungSoomin AhnEunyoung KangEun-Kyu KimSe Hyun KimJee Hyun KimIn Ah KimSo Yeon ParkPublished in: Journal of breast cancer (2019)
Changes in biomarker status are not rare, and usually occur in an unfavorable direction in breast cancer metastases. Negative conversion of ER status is a predictor of poor prognosis. Thus, it is beneficial to evaluate changes in biomarker status in MBC not only for the purpose of determining treatment options but also for prognostication of patients.